Turning the world’s most powerful biologics into pills

Turning the world’s most powerful biologics into pills

CapsulateBio is building the future of oral drug delivery systems that enable biologic medicines across molecular weights and therapeutic areas to be swallowed instead of injected. From peptides to monoclonal antibodies to nucleic acids, we're developing the next generation of oral therapeutics.

CapsulateBio is building the future of oral drug delivery systems that enable biologic medicines across molecular weights and therapeutic areas to be swallowed instead of injected. From peptides to monoclonal antibodies to nucleic acids, we're developing the next generation of oral therapeutics.

Supported by

Built on a breakthrough

CapsulateBio was founded on a breakthrough born in the Langer and Traverso Labs at MIT, where pioneering research laid the foundation for a new era of oral drug delivery. CapsulateBio's category-defining drug delivery platform is capable of reshaping how biologics are administered globally.

Headshot of co-founder Mark Ellis

Mark Ellis

Co-Founder & CEO

"Every once in a while you encounter a technology capable of creating an entirely new category. I believe CapsulateBio is one of those rare innovations redefining how biologic medicines are delivered so patients no longer have to choose between the most effective therapy and the most convenient one."

Headshot of co-founder Mark Ellis

Mark Ellis

Co-Founder & CEO

"Every once in a while you encounter a technology capable of creating an entirely new category. I believe CapsulateBio is one of those rare innovations redefining how biologic medicines are delivered so patients no longer have to choose between the most effective therapy and the most convenient one."

Headshot of co-founder Bob Langer Sc.D.

Bob Langer Sc.D.

Co-Founder & Scientific Advisor

"The most meaningful innovations are those that improve patients' lives at global scale, and I believe CapsulateBio represents one of the most exciting opportunities yet in my career to transform how biologic medicines are delivered."

Headshot of co-founder Bob Langer Sc.D.

Bob Langer Sc.D.

Co-Founder & Scientific Advisor

"The most meaningful innovations are those that improve patients' lives at global scale, and I believe CapsulateBio represents one of the most exciting opportunities yet in my career to transform how biologic medicines are delivered."

Headshot of co-founder Gio Traverso M.B., B.Chir., PhD.

Gio Traverso M.B., B.Chir., PhD.

Co-Founder & Scientific Advisor

"As both a physician and engineer, I've seen firsthand the burden injections place on patients, and CapsulateBio is the culmination of years of research to create a simpler, safer and more patient-centered way to deliver these medicines."

Headshot of co-founder Gio Traverso M.B., B.Chir., PhD.

Gio Traverso M.B., B.Chir., PhD.

Co-Founder & Scientific Advisor

"As both a physician and engineer, I've seen firsthand the burden injections place on patients, and CapsulateBio is the culmination of years of research to create a simpler, safer and more patient-centered way to deliver these medicines."

A new paradigm for oral biologic delivery

For decades, the gastrointestinal barrier has limited the oral delivery of biologics. Conventional oral technologies rely on chemical absorption enhancers that deliver less than 5% bioavailability, making them unsuitable for most biologics. CapsulateBio has created simple-to-swallow robotic pills.

CapsulateBio’s oral platforms are designed to do more than replace injections with a more convenient oral option. By enabling delivery of therapeutically relevant doses with injectable-like bioavailability, our platform has the potential to preserve and enhance the safety and efficacy of today’s leading biologics. This creates new opportunities to optimize dosing, improve patient adherence, reduce pharmacokinetic variability, and expand the therapeutic potential of biologics for patients worldwide.

CapsulateBio's CapsulateSI Oral Administration Platform
™

SI

SI

Capsulate

Capsulate

Oral Administration Platform

Delivers liquid biologics directly into the wall of the small intestine where conditions are ideal for systemic absorption, overcoming the gastrointestinal barrier that has long limited oral biologic delivery.

CapsulateBio's CapsulateST Oral Administration Platform
™

ST

ST

Capsulate

Capsulate

Oral Administration Platform

Delivers solid biologics directly into the wall of the stomach using a self-orienting robotic pill, overcoming the gastrointestinal barrier that has long limited oral biologic delivery.

Partner on the next generation of medicines

CapsulateBio is actively pursuing strategic collaborations with leading biopharmaceutical companies to unlock the full potential of biologic medicines across a broad range of therapeutic areas through our CapsulateSI™ oral delivery platform.

Our flexible partnership model enables collaborators to transform injectable therapies into convenient oral medicines, expand into new indications and patient populations, strengthen lifecycle management strategies, and accelerate the development of differentiated products. Together, we are redefining what is possible in oral biologic delivery and improving access for patients worldwide. If you are interested in discussing a strategic collaboration, let’s talk.

Two scientists working together and laughing
Scientist looking through microscope

Partner on the next generation of medicines

CapsulateBio is actively pursuing strategic collaborations with leading biopharmaceutical companies to unlock the full potential of biologic medicines across a broad range of therapeutic areas through our CapsulateSI™ oral delivery platform.

Our flexible partnership model enables collaborators to transform injectable therapies into convenient oral medicines, expand into new indications and patient populations, strengthen lifecycle management strategies, and accelerate the development of differentiated products. Together, we are redefining what is possible in oral biologic delivery and improving access for patients worldwide. If you are interested in discussing a strategic collaboration, let’s talk.

Two scientists working together and laughing
Scientist looking through microscope

Partner on the next generation of medicines

CapsulateBio is actively pursuing strategic collaborations with leading biopharmaceutical companies to unlock the full potential of biologic medicines across a broad range of therapeutic areas through our CapsulateSI™ oral delivery platform.

Our flexible partnership model enables collaborators to transform injectable therapies into convenient oral medicines, expand into new indications and patient populations, strengthen lifecycle management strategies, and accelerate the development of differentiated products. Together, we are redefining what is possible in oral biologic delivery and improving access for patients worldwide. If you are interested in discussing a strategic collaboration, let’s talk.

Two scientists working together and laughing
Scientist looking through microscope

Reinventing injection with a pill

© 2026 CapsulateBio

™

Reinventing injection with a pill

™

© 2026 CapsulateBio

™

Reinventing injection with a pill

© 2026 CapsulateBio

™

CapsulateBio